Perszyk, R.E., Yip, M.C., McConnell, O.L., Wang, E.T., Jenkins, A., Traynelis, S.F., & Forest, C.R. (2021). Automated Intracellular Pharmacological Electrophysiology for Ligand-Gated Ionotropic Receptor and Pharmacology Screening. Molecular Pharmacology, 100(1), 73 LP – 82. https://doi.org/10.1124/molpharm.120.000195[PDF]
Landry, C. R., Yip, M. C., Kolb, I., Stoy, W. M., Gonzalez, M. M. and Forest, C. R. (2021). Method for Rapid Enzymatic Cleaning for Reuse of Patch Clamp Pipettes: Increasing Throughput by Eliminating Manual Pipette Replacement between Patch Clamp Attempts. Bio-protocol 11(14): e4085. DOI: 10.21769/BioProtoc.4085.[PDF]
Gonzalez, M. M., Lewallen, C. F., Yip, M. C., & Forest, C. R. (2021). Machine Learning-Based Pipette Positional Correction for Automatic Patch Clamp In Vitro. ENeuro, 8 (August), 1–8. doi: https://doi.org/10.1523/ENEURO.0051-21.2021[PDF]
M.C. Yip, M.M. Gonzalez, C.R. Valenta, M.J.M. Rowan, C.R. Forest. Deep learning-based real-time detection of neurons in brain slices for in vitro physiology. Sci Rep 11, 6065 (2021). https://doi.org/10.1038/s41598-021-85695-4[PDF]
Timothy J. Lee, Mighten C. Yip, Aditi Kumar, Colby F. Lewallen, Daniel J. Bumbarger, R. Clay Reid and Craig R. Forest, Capillary-Based and Stokes-Based Trapping of Serial Sections for Scalable 3D-EM Connectomics, eNeuro 24 February 2020, 7 (2) ENEURO.0328-19.2019; DOI: https://doi.org/10.1523/ENEURO.0328-19.2019[PDF]
Colby F. Lewallen, Qin Wan, Arvydas Maminishkis, William Stoy, Ilya Kolb, Nathan Hotaling, Kapil Bharti, and Craig R. Forest, High-yield, automated intracellular electrophysiology in retinal pigment epithelia, Journal of Neuroscience Methods, Volume 328, 2019, 108442, ISSN 0165-0270, https://doi.org/10.1016/j.jneumeth.2019.108442.[PDF]
G.L. Holst, W. Stoy, B. Yang, I. Kolb, S.B. Kodandaramaiah, L. Li, U. Knoblich, H. Zeng, B. Haider, E.S. Boyden, C.R. Forest, Autonomous patch clamp robot for functional characterization of neurons in vivo: development and application to mouse visual cortex, J. Neurophysiology 121:2341- 2357, 2019. https://doi.org/10.1152/jn.00738.2018[PDF]
Kolb, I., Landry, C. R., Yip, M. C., Lewallen, C. F., Stoy, W. A., Lee, J., Felouzis, A., Yang, B., Boyden, E. S., Rozell, C. J., & Forest, C. R. (2019). PatcherBot: a single-cell electrophysiology robot for adherent cells and brain slices. Journal of neural engineering, 16(4), 046003. https://doi.org/10.1088/1741-2552/ab1834[PDF]
I.K. Cho, B. Yang, C.R. Forest, L. Qian, A.W.S. Chan, Amelioration of Huntington’s disease phenotype in astrocytes derived from iPSC-derived neural progenitor cells of Huntington’s disease monkeys, PLOS One 14(3): e0214156. https://doi.org/10.1371/journal.pone.0214156[PDF]
T.J. Lee, A. Kumar, A.H. Balwani, D. Brittain, S. Kinn, C.A. Tovey, E.L. Dyer, N.M. da Costa, R.C. Reid, C.R. Forest*, D.J. Bumbarger* (*co-corresponding authors). Large-scale neuroanatomy using LASSO: Loop-based Automated Serial Sectioning Operation, PLOS One 13(10): e0206172. https://doi.org/10.1371/journal.pone.0206172 (2018)[PDF]
T.J. Lee, C.F. Lewallen, D.J. Bumbarger, P.J. Yunker, R.C. Reid, C.R. Forest. Transport and trapping of nanosheets via hydrodynamic forces and curvature-induced capillary quadrupolar interactions, Journal of Colloid and Interface Science (2018). DOI: 10.1016/j.jcis.2018.07.068[PDF]
M.T. Morgan, B. Yang, S. Harankhedkar, A. Nabatilan, D. Bourassa, A.M. McCallum, F. Sun. R. Wu, C.R. Forest, C.J. Fahrni, Stabilization of aliphatic phosphines by auxiliary phosphine sulfides offers zeptomolar affinity and unprecedented selectivity for probing biological Cu(I), Angew. Chem. 10.1002/ange.201804072[PDF]
J. Lee, I. Kolb, C.R. Forest, C.J. Rozell, Cell membrane tracking in living brain tissue using differential interference contrast microscopy, IEEE Transactions on image processing, 2018 Apr; 27(4):1847-1861. doi: 10.1109/TIP.2017.2787625.
I. Kolb, G.T. Franzesi, M. Wang, S.B. Kodandaramaiah, C.R. Forest, E.S. Boyden, A.C. Singer, Evidence for long-timescale patterns of synaptic inputs in CA1 of awake behaving mice, Journal of Neuroscience 26 December 2017, 1519-17; DOI: https://doi.org/10.1523/JNEUROSCI.1519-17.2017[PDF]
S.B Kodandaramaiah, F. Flores, G. Holst , A. Singer , X. Han , E. Brown , E. Boyden, C.R. Forest, Multi-neuron intracellular recording in vivo via interacting autopatching robots, eLife 2018;7:e24656 DOI: 10.7554/eLife.24656[PDF]
B. Krishnaswamy, Y. Jian, C.M. Austin, J.E. Perdomo, S.C. Patel, B.K. Hammer, C.R. Forest, R. Sivakumar, ADMA: Amplitude-Division Multiple Access for Bacterial Communication Networks, Institute of Electrical and Electronics Engineers (IEEE) Transactions on Molecular, Biological, and Multi-Scale Communications, DOI: 10.1109/TMBMC.2018.2791448[PDF]
H.-J. Suk, I. vanWelie, S.B. Kodandaramaiah, B. Allen, C.R. Forest, E.S. Boyden, Closed-loop, real-time imaging enables fully automated cell-targeted patch-clamp neural recording in vivo, Neuron, V. 95(5), 30 August 2017, Pages 1037-1047.e11 DOI: https://doi.org/10.1016/j.neuron.2017.08.011 PMCID: PMC5586501[PDF]
C. Austin , D. Caro , S. Sankar , W. Penniman , J. Perdomo , L. Hu , S. Patel , X. Gu , S. Watve, B. Hammer, C.R. Forest, Porous monolith microfluidics for bacterial cell-to-cell communication assays, Biomicrofluidics 11, 044110 (2017); doi: http:///dx.doi.org/10.1063/1.4995597[PDF]
W.A. Stoy, I. Kolb, G.L. Holst, Y. Liew, A. Pala, B. Yang, S.B. Kodandaramaiah, E.S. Boyden, G.B. Stanley, C.R. Forest, Robotic navigation to sub-cortical neural tissue for single cell electrophysiology in vivo, J. Neurophysiology, 7 June 2017, doi: 10.1152/jn.00117.2017[PDF]
L. Li, B. Ouellette, W. Stoy, E. Garren, T.L. Daigle, C.R. Forest, C. Koch, H. Zeng, A robot for high yield electrophysiology and morphology of single neurons in vivo, Nature Communications, 15604 (2017), doi:10.1038/ncomms15604[PDF]
P.Y. Borden, A.D. Ortiz, C. Waiblinger, A.J. Sederberg, A.E. Morrissette, C.R. Forest, D. Jaeger, G.B. Stanley, Genetically expressed voltage sensor ArcLight for imaging large scale cortical activity in the anesthetized and awake Mouse, Neurophotonics, 4(3), 031212 (2017), doi: 10.1117/1.NPh.4.3.031212[PDF]
M.A. Stockslager*, C.M. Capocasale* (*co-first authors), G.L. Holst, M.D. Simon, Y. Li, D.J. McGruder, E.B. Rousseau, W.A. Stoy, T. Sulchek, C.R. Forest, Optical method for automated measurement of glass micropipette tip geometry, Precision Engineering, Vol 46, p. 88-95, October 2016.
S.B. Kodandaramaiah, G.B. Holst, I.R. Wickersham, A.C. Singer, G.T. Franzesi, M. McKinnon, C.R. Forest, E.S. Boyden, Assembly and operation of an autopatcher: a robot for automated intracellular neural recording in vivo, Nature Protocols, 11, 634-654 (2016). doi:10.1038/nprot.2016.007
M.A. Stockslager, B.C. Samuels, R.R. Allingham, Z.A. Klesmith, S.A. Schwaner, C.R. Forest, C.R. Ethier, System for rapid, precise modulation of intraocular Pressure, toward minimally-invasive in vivo measurement of intracranial pressure, PLoS One, 2016 Jan 15;11(1):e0147020. doi: 10.1371/journal.pone.014702
I. Kolb, W.A. Stoy, E. Rousseau, O.A. Moody, A. Jenkins, C.R. Forest, Cleaning patch-clamp pipettes for immediate reuse, Scientific Reports 6: 35001, 2016. doi:10.1038/srep35001 (over 10 articles in popular press, example below in D.21, Altmetric score in 97th percentile of 133,000 articles of similar age in all journals)
Q. Wu*, I. Kolb* (*co-first authors), B.M. Callahan, Z. Su, W. Stoy, S.B. Kodandaramaiah, R. Neve, H. Zeng, E.S. Boyden, C.R. Forest#, A.A. Chubykin# (#co-corresponding authors), Integration of autopatching with automated pipette and cell detection in vitro, J. Neurophysiology (in press). doi: 10.1152/jn.00386.2016
Y. Ouyang, J. Li, C. Phaneuf, P. Riehl, C. Forest, M. Begley, D. Haverstick, J. Landers, Multilevel fluidic flow control in a rotationally-driven polyester film microdevice created using laser print and cut, Lab on a Chip, Vol. 16, p. 377-387, Jan 2016.
C.R. Phaneuf, N. Pak, D. C. Saunders, G.L. Holst, J. Birjiniuk, N. Nagpal, S. Culpepper, E. Popler, A.L. Shane, R.C. Jerris, C.R. Forest, Thermally multiplexed polymerase chain reaction, Biomicrofludics, Vol. 9, 044117 (2015). (Selected as one of the Editor’s Picks, 2015)
O. Bizen, C.M. Austin, I. Akyildiz, C.R. Forest, Efficient sampling of bacterial signal transduction for detection of pulse-amplitude modulated molecular signals, Institute of Electrical and Electronics Engineers (IEEE) Transactions on Biomedical Circuits and Systems, Vol. 9(4), p. 505-517, August 2015.
M.V. Baratta, S.B. Kodandaramaiah, P.E. Monahan, P.-A. Lin, K. Kim, A. Yang, C.R. Forest, E.S. Boyden, K.A. Goosens, Stress enables reinforcement-elicited serotonergic consolidation of fear memory, Biological Psychiatry, 2015 Jul 2, doi: 10.1016/j.biopsych.2015.06.025
R.R. Harrison, I. Kolb, S.B. Kodandaramaiah, A.A. Chubykin, A. Yang, M.F. Bear, E.S. Boyden, C.R. Forest, Microchip amplifier for in vitro, in vivo, and automated whole-cell patch-clamp recording, J. Neurophysiology
C.R. Forest, R.A. Moore, B.B. Fasse, A.S. Jariwala, B.B. Fasse, J. Linsey, W. Newstetter, P. Ngo, C. Quintero, The Invention Studio: a university maker space and culture, Advances in Engineering Education, Vol. 4(2) (Fall 2014).
E.A. Tyburski, S.E. Gillespie, W.A. Stoy, R.G. Mannino, A.J. Weiss, A.F. Siu, R.H. Bulloch, K. Thota, A. Cardenas, W. Session, H.J. Khoury, S. O’Connor, S.T. Bunting, J. Boudreaux, C.R. Forest, M. Gaddh, T. Leong, T. Leong, L.A. Lyon, W.A. Lam, Disposable platform provides visual and color-based point-of-care anemia self-testing, The Journal of Clinical Investigation, August 2014.
A.S. Chuong, M.L. Miri, L.C. Acker, S.B. Kodandaramaiah, M.A. Henninger, M. Ogawa, R.C. Bandler, N.C. Klapoetke, X. Gu, B.D. Allen, C.R. Forest, B.Y. Chow, X. Han, J.A. Cardin, E.S. Boyden, Noninvasive optical inhibition with a red-shifted microbial rhodopsin, Nature Neuroscience. Vol 17, p. 1123-1129, July 2014.
M. Li, N.A. Hotaling, D.N. Ku, C.R. Forest, Microfluidic thrombosis under multiple shear rates and platelet therapy doses, PLOS ONE (Also, B.b.56)
C.M. Austin, W. Stoy, P. Su, M.C. Harber, J.P. Bardill, B.K. Hammer, C.R. Forest, Modeling and validation of autoinducer-mediated bacterial gene expression in microfluidic environments, Biomicrofluidics, Vol. 8, 034116 (2014).
B. Krishnaswamy, C.M. Henegar, J.P. Bardill, D. Russakow, G.L. Holst, B.K. Hammer, C.R. Forest, R. Sivakumar, Time-elapse communication for bacterial communication on a microfluidic chip, Time Elapse Communication for Super-Slow Networks, Institute of Electrical and Electronics Engineers (IEEE) Transactions on Networking (Also, B.b.54)
S.B. Kodandaramaiah, E.B. Boyden, C.R. Forest, in vivo robotics: Towards the automation of neuroscience and other intact-system biological fields, Annals of the New York Academy of Sciences (in press doi: 10.1111/nyas.12171).
D.C. Saunders, G.L. Holst, C.R. Phaneuf, N. Pak, M. Marchese, N. Sondej, M. McKinnon, C.R. Forest, Rapid, quantitative, reverse transcription PCR in a polymer microfluidic chip, Biosensors and Bioelectronics, Vol. 44, p. 222-228, June 2013.
N. Hotaling, B.B. Fasse, F. Bost, C. Hermann, C.R. Forest, A quantitative analysis of the effects of a multi-disciplinary engineering capstone design course, Journal of Engineering Education, Vol. 101(4), p. 630-656, October 2012.[PDF]
I.F Akyildiz, F. Fekri, C.R Forest, B. Hammer, R. Sivakumar, MONACO: Fundamentals of Molecular Nano-Communication Networks (Invited Paper), IEEE Wireless Communications, Special Issue on Wireless Communications at the Nano-Scale, Vol. 19(5), p. 12-18, October 2012.[PDF]
C.R. Phaneuf, K. Oh, N. Pak, D.C. Saunders, C. Conrardy, J. Landers, S. Tong, C.R. Forest, Sensitive, microliter PCR with consensus degenerate primers for Epstein Barr virus, Biomedical Microdevices, Vol. 14(6), p. 1-11, Oct 2012.[PDF]
S. Kodandaramaiah, G. Franzesi, B. Chow, E. Boyden, C.R. Forest, Automated whole-cell patch clamp electrophysiology of neurons in vivo, Nature Methods. Vol 9, p. 585–587, May 2012.[PDF]
N. Pak, C. Saunders, C.R. Phaneuf, C.R. Forest, Plug-and-play infrared laser-mediated PCR in a microfluidic chip, Biomedical Microdevices. Vol. 14(2), p. 427-433, April 2012.[PDF]
M. Li, D. Ku, C.R. Forest, Microfluidic system for simultaneous optical measurement of platelet aggregation at multiple shear rates in whole blood, Lab on a Chip, Vol 12, p. 1355-1362, February 2012.[PDF]
N. Pak, M. Dergance, M. Emerick, E. Gagnon, C.R. Forest, An Instrument For Controlled, Automated, Continuous Production of Micrometer Scale Fused Silica Pipettes, ASME Journal of Mechanical Design, Vol. 133(6), 061006, June 2011.[PDF]
C.R. Phaneuf, N. Pak, C.R. Forest, Modeling radiative heating of liquids in microchip reaction chambers, Sensors and Actuators: A. Physical, Vol. 167(2), p. 531-536, February 2011.[PDF]
H.H. Wang, F.J. Isaacs, P.A. Carr, Z.Z. Sun, G. Xu, C.R. Forest, G.M. Church, Programming cells by multiplex genome engineering and accelerated evolution, Nature, Vol. 460, p. 894-898, July 2009.[PDF]
C.R. Forest, M.A. Saez, I.W. Hunter, Microforging Technique for Rapid, Low-cost Fabrication of Lens Array Molds, Applied Optics, Vol 46(36), p. 8668-8673, December 2007 (featured on cover)[PDF]
C.R. Forest, B. Woodruff, D. Buckley, W.G. Thilly, and I.W. Hunter, Assembly and Constraint Technology for Large Arrays of Capillaries, Precision Engineering, Vol 33(3), p. 275-283, July 2007.[PDF]
M. Akilian, C.R. Forest, A.H. Slocum, D.L. Trumper, and M.L. Schattenburg, Thin Optic Constraint, Precision Engineering, Vol 31(2), p. 130-138, April 2007.[PDF]
C.R. Forest, M. Spenko, Y. Sun, A.H. Slocum, R.K. Heilmann and M.L. Schattenburg, Repeatable and accurate assembly of x-ray foil optics, Precision Engineering, Vol 30(1), p. 63-70, January 2006.
C.R. Forest, C.R. Canizares, D.R. Neal, M. McGuirk, and M.L. Schattenburg, Metrology of thin transparent optics using Shack-Hartmann wavefront sensing, Optical Engineering, Vol. 43(3), p. 742-753, March 2004.[PDF]
Y. Sun, R.K. Heilmann, C.G. Chen, C.R. Forest and M.L. Schattenburg, Precision microcomb design and fabrication for x-ray optics assembly, Journal of Vacuum Science and Technology B, Vol. 21(6), p. 2970-2974, November/December 2003.[PDF]